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SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

1. Review the following procedure code:
proc ttest data=DATA1;
class GROUPVAR1;
var VAR1;
run;
Which variable is most appropriate to be analyzed as variable VAR1?

A) Treatment, with possible values of "Placebo" or "Active"
B) Age, with possible values of any integer between and including 18 and 65
C) Number of infections, with possible values of 0, 1, or 2
D) Systolic blood pressure, with possible values of "<120", "120 - 139", "140 - 159", "160 - 179", and
"180+"

2. Given the file sites.csv:

Which option would you need to add to the INFILE statement to clear the notes from this log?

A) firstobs=2
B) lrecl=2
C) start=2
D) missover

3. This question will ask you to provide a line of missing code. Given the data set RAWBP that is sorted by SUBJECT TEST WEEK:

The following SAS program is submitted:
data bp;
set rawbp;
by subject test week;
retain baseline;
if first.test then baseline = .;
if week = 0 then baseline = value;
else if week > 0 then do;
<insert code here>
end;
run;
Which statement must be added to the program to calculate percent change from baseline?

A) pct_chg = ((baseline - value) /baseline)*100;
B) pct_chg = ((baseline - value) /value)*100;
C) pct_chg = ((value - baseline) /value)*100;
D) pct_chg = ((value - baseline) /baseline)*100;

4. When writing a validation program using independent programming, which two actions conform to good programming practices?
(Choose two.)

A) Copy statistical code directly from the production program.
B) Copy statistical code directly from the SAP.
C) Delete subjects from the production side that are causing differences with the validation data set.
D) Ensure the production program has been run prior to compare.

5. Which statement correctly describes an aspect of a Phase II clinical trial?

A) designed to assess the pharmacovigilance, pharmacokinetics, and pharmacodynamics of a drug
B) randomized controlled multicenter trials on large patient groups
C) in vitro and in vivo experiments using wide-ranging doses of the drug
D) designed to assess how well the drug works

Solutions: